Genetics From Genes to Genomes Study Set 1

Biology

Quiz 7 :
Anatomy and Function of a Gene: Dissection Through Mutation

Quiz 7 :
Anatomy and Function of a Gene: Dissection Through Mutation

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In a segment of DNA, an A base is changed to a C and the error is copied during replication.Under which circumstances is that change considered a mutation? (Select all that apply. )
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A, B, C, D

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Replacing a thymine nucleotide with a guanine is an example of a
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C

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Replacing an adenine nucleotide with a guanine is an example of a
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B

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Assume that a wild-type sequence is 5' AGCCTAC 3'.Which sequence could be produced by a transversion?
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Assume that the mutation rate for a given gene is 5 × 10−6 mutations per generation.For that gene, how many mutations would be expected if 10 million sperm are examined?
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Which type of mutation is least likely to revert?
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When Luria and Delbruck assayed bacterial growth on the petri plates, what did they find?
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In the Luria Delbruck experiment, what did the appearance of a bacterial colony on a petri plate indicate?
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What did the results of the Luria Delbruck fluctuation experiment indicate?
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A researcher planned to duplicate the Luria Delbruck fluctuation experiment.This researcher inoculated twenty samples of liquid nutrient media with bacteria from the same colony and let them grow overnight.The next morning the researcher noticed that all but one of the flasks had come open and were ruined.Not wishing to redo the experiment, the researcher spread samples of bacteria from the one intact liquid culture on twenty petri plates that had nutrient agar infused with bacteriophage.What results do you expect the researcher obtained from this experiment?
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What does the hydrolysis of a purine base from the deoxyribose-phosphate backbone leave behind?
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Thymine dimers are caused by
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Exposure to UV light from the sun or tanning beds causes
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The heritable disorder fragile X syndrome, a major cause of intellectual disability, is caused by
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If a man has one premutation allele for fragile X syndrome, what is the probability that he will pass the premutation allele on to his son?
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The base analog 5-bromouracil can tautomerize.One tautomer behaves like thymine and the other behaves like cytosine.If 5-bromouracil is used as a mutagen, what is the minimum number of times replication must occur to mutate the codon for proline (CCC)into the codon for alanine (GCC)?
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The base analog 5-bromouracil can tautomerize.One tautomer behaves like thymine and the other behaves like cytosine.If 5-bromouracil is used as a mutagen, what is the minimum number of times replication must occur to mutate the codon for proline (CCC)into the codon for serine (TCC)?
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Intercalating agents, such as acridine orange, are mutagens because they
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Alkylating agents, such as ethylmethane sulfate (EMS), are mutagens because they
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In a test tube, a particular DNA polymerase has an error rate of 1 mistake in every 106 bases copied.Why is the mutation rate in a cell that uses this DNA polymerase much lower?
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