Genetics From Genes to Genomes Study Set 1

Biology

Quiz 20 :
The Genetics of Cancer

Quiz 20 :
The Genetics of Cancer

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The enzymatic activity of CDKs is regulated by forming a complex with which proteins?
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D

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Which statement best describes the action of polypeptide growth factors?
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B

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The retinoblastoma (Rb)protein controls progression into S phase by regulating ________ activity.
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D

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The activity of Rb is controlled by
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Which of the following is not likely to occur if p53 is inactivated?
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A cellular process that results in cell death is
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Which characteristic is typical of a cancer cell but not of a normal cell?
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The enzyme telomerase is essential for unlimited cell division because
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A karyotype of chromosomes from a cancer cell would be most likely to exhibit
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The ability of a cell to move from the tissue to which it belongs to other parts of the body is known as
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The current model of cancer development is that
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In its active form, the Ras protein is associated with
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What is one piece of evidence that supports the hypothesis that cancers are clonal?
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What is the term for mutant alleles that can act dominantly to predispose a cell to a cancerous phenotype?
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How can a mutation in a tumor-suppressor gene behave as a recessive allele at the cellular level, but appear as a dominant allele in pedigree analysis?
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The human papillomavirus (HPV)carries a gene that functions as an oncogene by inactivating the p53 protein.The fact that the loss of p53 function is oncogenic suggests that
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The BRCA2 protein functions in double-strand break repair.If a woman is heterozygous for a loss-of-function allele of BRCA2, she
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What is the relationship between genomic instability and proliferation?
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Drugs such as Gleevec® and Herceptin® represent a modern approach to cancer treatment because they
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What is one reason why tumor-suppressor genes make poor druggable targets?
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