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Genetics From Genes to Genomes Study Set 1

Biology

Quiz 10 :

Genome Annotation

Quiz 10 :

Genome Annotation

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How do the genes in the β-globin locus differ from each other?
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B

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Which of the following is a potential mechanism through which proteins can acquire novel domain architectures over evolutionary time?
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B

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Which of the following processes can generate orthologous genes over evolutionary time?
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C

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A BLAST search can be used for which of these applications?
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A student analyzes a genomic DNA sequence of 100 nucleotides in order to determine if it is part of a gene.When she translates the sequence beginning at the first nucleotide, she finds that the tenth codon is UAA.What should she do next?
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What do you predict would be the effect of an inversion of the β-globin gene cluster with respect to the LCR?
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Pseudogenes are evidence of
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How are open reading frames or exons predicted from genomic sequence?
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Reverse transcriptase is an enzyme encoded in the genomes of
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Use the BLAST tool at http://blast.ncbi.nlm.nih.gov/Blast.cgi and click "Protein blast" to find out the identity of the protein with the following amino acid sequence: CCKHPEAKRM PCAEDYLSVV LNQLCVLHEK TPVSDRVTKC CTESLVNRRP
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What is a RefSeq?
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What is one way that genes can be predicted in genome sequences?
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Which piece of evidence is most likely to indicate a gene within a genome?
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Which of the following is a way that protein function can be modified AFTER translation?
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Which experiment would best determine which genes are expressed in a Drosophila embryo?
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What information cannot be determined from the DNA sequence of a cDNA clone?
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Which disease results from deletion of the β-globin gene cluster LCR?
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Which enzyme copies an mRNA sequence into DNA during cDNA library construction?
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Approximately what proportion of the human genome is composed of the exome?
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What is the advantage of having different forms of hemoglobin?
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