Genetics From Genes to Genomes Study Set 1

A crucial step in the regulation of most bacterial genes occurs

What would be the phenotype of a null mutation in the gene encoding Lac repressor?

Transcription and translation can be coupled in bacteria but not eukaryotes because

How do negative regulators such as the Lac repressor prevent RNA polymerase from initiating transcription?

How does a positive regulator affect transcription by RNA polymerase in prokaryotes?

Proteins whose conformations change when they are bound to an effector molecule are called

Catabolic pathways that break down complex substances into more usable units are usually regulated in response to the

Anabolic pathways involved in the synthesis of essential molecules are usually regulated in response to

Which statement accurately describes global gene regulation in bacteria?

How is glucose involved in catabolite repression of the lac operon?

The function of a helix-turn-helix motif in a transcription factor is to

How does tryptophan, the end product of the trp operon, function in the regulation of the operon?

What term describes regulation of the trp operon that can occur even in trpR− mutants, thus suggesting that the mechanism is repressor-independent?

In E.coli the heat shock response, which alters the proteins produced by the cell at different temperatures, is mediated by

As a general principle of gene regulation through operons, regulatory genes encode

In the trp operon, attenuation occurs through translation of two Trp codons in the leader sequence.What would happen if these two codons were mutated to stop codons?

Initiation of transcription by RNA polymerase involves the binding of which of the following subunits to the core enzyme?

The transition from transcriptional initiation to elongation involves

Which molecules are examples of effector molecules?

A single DNA unit that enables the simultaneous regulation of more than one coding region in response to environmental changes is called a(n)