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Human Pharmacology

Nursing

Quiz 22 :

Antiarrhythmic Drugs

Quiz 22 :

Antiarrhythmic Drugs

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The class III drug amiodarone:
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Multiple Choice
Answer:

Answer:

E
Amiodarone has an extremely complex and incompletely understood spectrum of actions. It blocks several K+ channels. It blocks both Na+ and Ca++ channels (class I and IV effects) and is a noncompetitive β receptor antagonist (class II effect).

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The mechanism of action of class III antiarrhythmic drugs is:
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Multiple Choice
Answer:

Answer:

B
The electrophysiologic action of class III antiarrhythmics includes the blockade of one or more of the three types of potassium channels involved in phase 3 of the action potential of myocardial cells.

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The action potential of a myocardial pacemaker cell differs from that of the non-pacemaker cell in that:
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Multiple Choice
Answer:

Answer:

E
The myocardial pacemaker cell's sodium channels are inactivated. Calcium influx is the initiator of the depolarization that results in a slow, more prolonged action potential.