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Human Pharmacology

Nursing

Quiz 26 :

Antithrombotic Drugs

Quiz 26 :

Antithrombotic Drugs

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Heparin differs from low molecular weight heparins (LMWH) in that:
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Multiple Choice
Answer:

Answer:

C
Low molecular weight heparins inhibit Xa more than thrombin and therefore have a milder effect on PTT; thus they can safely be used by outpatients.

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Two vitamin K-dependent factors made in the liver are proteins C and S.
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Multiple Choice
Answer:

Answer:

C
Proteins C and S normally inhibit excessive coagulation in their active state. They inhibit the formation of fibrin from fibrinogen. However, they are not used as thrombolytics in the treatment of MI and stroke. Warfarin inhibits the formation of proteins C and S and can cause paradoxical hypercoagulability when first administered.

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Warfarin administration:
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Multiple Choice
Answer:

Answer:

C
The coumarin class of drugs inhibits vitamin K-dependent clotting factors. Only an infusion of fresh frozen plasma can quickly reverse the anticoagulant effect. However, PO vitamin K can be used when time allows.