Quiz 2: Pharmacokinetics Idrug Administration,absorption,and Distribution
Nursing
Q 1Q 1
All of the following are parenteral routes of drug administration EXCEPT the ____ route.
A)oral
B)inhalation
C)injection
D)topical
E)transdermal
Free
Multiple Choice
A
Q 2Q 2
The ______ effect occurs when drugs are initially transported to the liver where a significant amount of the drug may be metabolized and destroyed before the drug reaches its primary site of action.
A)malabsorptive
B)first-pass
C)Bohr
D)bioequivalence
E)pharmacodynamic
Free
Multiple Choice
B
Q 3Q 3
Iontophoresis,phonophoresis,and medicated patches all use the _____ route to administer drugs.
A)oral
B)inhalation
C)injection
D)transdermal
E)rectal
Free
Multiple Choice
D
Q 4Q 4
This first-pass effect is of particular concern when drugs are administered:
A)topically.
B)intravenously.
C)subcutaneously.
D)by inhalation.
E)orally.
Free
Multiple Choice
Q 5Q 5
The extent to which a drug reaches the systemic circulation is referred to as:
A)bioequivalence.
B)biotransformation.
C)bioavailability.
D)biodistribution.
E)last-pass metabolism.
Free
Multiple Choice
Q 6Q 6
When crossing cell membranes,drugs will diffuse more readily through the lipid layer if they are:
A)nonlipid soluble.
B)in a neutral,nonionized form.
C)in a charged,ionized form.
D)large proteins.
E)none of the above
Free
Multiple Choice
Q 7Q 7
Osmosis refers to the special case of diffusion where the diffusing substance is:
A)a lipid-soluble drug.
B)a nonlipid-soluble drug.
C)a protein.
D)a carbohydrate.
E)water.
Free
Multiple Choice
Q 8Q 8
Carrier specificity,expenditure of energy,and ability to transport substances against a concentration gradient are all characteristics of:
A)simple,passive diffusion.
B)facilitated diffusion.
C)active transport.
D)endocytosis.
E)exocytosis.
Free
Multiple Choice
Q 9Q 9
A drug that has a volume of distribution of approximately 42 L will typically be:
A)bound extensively to plasma proteins.
B)retained in the bloodstream.
C)concentrated in the tissues.
D)stored in the liver and kidneys.
E)uniformly distributed throughout all of the body fluids.
Free
Multiple Choice
Q 10Q 10
The primary site for drug storage in the body is:
A)muscle.
B)bone.
C)skin.
D)adipose tissue.
E)the brain.
Free
Multiple Choice