Binding energy between an enzyme and a substrate contributes to catalysis in which way?
A) Binding energy provides the enzyme specificity for the substrate.
B) Binding energy contributions allow for entropy reduction in the substrate-enzyme complex.
C) Binding energy compensates for energy changes as a result of desolvation of the substrate.
D) Binding energy contributes to the process of induced fit between the substrate and the enzyme.
E) All of the answers are correct.

Question

Quizplus · Accepted Answer

All of the choices are correct. Binding energy helps in creating a more stable transition state which leads to a lower energy of activation required for the reaction. It also provides specificity for the substrate and assists in the process of induced fit between the enzyme and substrate. Furthermore, it reduces the entropy of the substrate-enzyme complex and compensates for energy changes as the substrate is desolvated.

Binding Energy Between an Enzyme and a Substrate Contributes to Catalysis