Which of the following is most consistent with a defective malate-aspartate shuttle
A) Abnormally large rise in glucose consumption when oxygen is admitted to an anaerobic incubation of tissue
B) Diminished ability of mitochondria to oxidize isocitrate
C) Large increase in the pyruvate:lactate ratio following exercise
D) Abnormally large decrease in intracellular pH of muscle during exercise
E) Partial uncoupling of oxidative phosphorylation

Question

Quizplus · Accepted Answer

The Answer of Which of the following is most consistent with a defective malate-aspartate shuttle
A) Abnormally large rise in glucose consumption when oxygen is admitted to an anaerobic incubation of tissue
B) Diminished ability of mitochondria to oxidize isocitrate
C) Large increase in the pyruvate:lactate ratio following exercise
D) Abnormally large decrease in intracellular pH of muscle during exercise
E) Partial uncoupling of oxidative phosphorylation

Which of the Following Is Most Consistent with a Defective