In the case of an enzyme displaying a sigmoid relationship between velocity and substrate concentration, it can be concluded that
A) the binding of one substrate molecule hinders the binding of others.
B) the enzyme contains only one binding site for substrate.
C) substrate binds more easily at low concentrations than at high concentrations.
D) the enzyme must contain at least four subunits.
E) the enzyme displays cooperativity in terms of substrate binding.

Question

Quizplus · Accepted Answer

A sigmoid relationship between velocity and substrate concentration indicates cooperativity in terms of substrate binding. This means that the binding of one substrate molecule enhances the binding of others, leading to an increase in velocity. This type of relationship is often seen in enzymes that have multiple subunits or domains that can interact with substrate molecules. Option A, B, C, and D are incorrect because they do not describe a sigmoid relationship between velocity and substrate concentration.

In the Case of an Enzyme Displaying a Sigmoid Relationship