Which of the following represents a protein modification which changes enzyme activity in a non-reversible manner?
A) Competitive inhibition
B) Zymogen activation
C) Phosphorylation of a serine residue of the protein
D) coenzyme activation
E) allosteric activation

Question

Quizplus · Accepted Answer

Zymogen activation is a process where an inactive enzyme precursor, or zymogen, is converted into an active enzyme. This conversion often involves the irreversible cleavage of specific peptide bonds within the zymogen, leading to a permanent change in the enzyme's structure and activity. Unlike reversible modifications such as phosphorylation or allosteric regulation, once a zymogen is activated, it cannot return to its inactive precursor form.

Which of the Following Represents a Protein Modification Which Changes