The complementarity-determining regions (CDR) of human immunoglobulin G
A) are common to the general structure of all immunoglobulin domains.
B) consist of short segments of highly variable amino acid sequence.
C) form covalent complexes with antigens.
D) have been identified only on the light chain polypeptides.
E) participate in the binding of these proteins to cell surface receptors.

Question

Quizplus · Accepted Answer

The complementarity-determining regions (CDR) of human immunoglobulin G consist of short segments of highly variable amino acid sequence. They are located on the antigen-binding fragment of the antibody molecule and are responsible for the specificity of the antibody's interaction with its antigen. The CDRs are diverse and unique to each individual's immune system, allowing for recognition of a wide range of antigens.

The Complementarity-Determining Regions (CDR) of Human Immunoglobulin G