Which of the following results in a shift of the oxyhemoglobin dissociation curve to the right? A) An increase in 2,3-BPG B) A decrease in temperature C) An increase in pH D) A decrease in PC0₂

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An increase in 2,3-BPG (2,3-bisphosphoglycerate) shifts the oxyhemoglobin dissociation curve to the right, which means that hemoglobin releases oxygen more readily in tissues with high metabolic rates. This is because 2,3-BPG decreases the affinity of hemoglobin for oxygen, allowing it to be more easily offloaded in tissues where it is needed. Conversely, a decrease in 2,3-BPG shifts the curve to the left, causing hemoglobin to hold onto oxygen more tightly. Temperature, pH, and PCO2 do affect the curve, but they do so in different ways.

Which of the Following Results in a Shift of the Oxyhemoglobin