All of the following are correct with respect to human IgE EXCEPT
A) the IgE heavy chain has 5 constant region domains.
B) IgE binds tightly to mast cell membranes.
C) the serum concentration of IgE is quite low when compared to the other immunoglobulins.
D) food-specific IgE is associated with true food allergies.
E) the reaction of a food antigen with mast cell membrane-bound IgE leads to the release of histamine and leukotrienes.

Question

Quizplus · Accepted Answer

IgE has 4 constant region domains in its heavy chain, not 5. This is a key structural characteristic that differentiates it from other immunoglobulin classes, such as IgM, which does have 5 constant region domains.

All of the Following Are Correct with Respect to Human