Which of the following statements is true regarding the role of NMDA receptors in mediating LTP in the brain?
A)NMDA receptors are critical to inducing LTP but not to maintaining LTP.
B)NMDA receptors block LTP in the brain unless magnesium ions are present.
C)NMDA receptors are depolarized by the binding of the neurotransmitter acetylcholine.
D)NMDA receptors create LTP by transporting magnesium ions from outside the cell into the cell.

Question

Quizplus · Accepted Answer

NMDA receptors are critical in inducing LTP, but not necessarily in maintaining it. Once LTP has been established, other mechanisms such as changes in gene expression or protein synthesis maintain the strengthened connections between neurons.

Which of the Following Statements Is True Regarding the Role