Imagine that a new drug is discovered that acts by depleting the brain of free magnesium ions. How would this drug affect long-term potentiation (LTP)?
A)The amount of LTP would increase.
B)The amount of LTP would decrease.
C)The amount of LTP would not change.
D)The amount of LTP would first decrease, then increase.

Question

Quizplus · Accepted Answer

Long-term potentiation (LTP) is a process involved in the strengthening of synaptic connections, which is crucial for learning and memory. A key step in the induction of LTP is the influx of calcium ions (Ca2+) through NMDA receptors, which are normally blocked by magnesium ions (Mg2+). If a drug depletes the brain of free magnesium ions, NMDA receptors would be less blocked, allowing more calcium to enter neurons and potentially increasing the amount of LTP.

Imagine That a New Drug Is Discovered That Acts by Depleting