Which of the following represents a major target tissue for the action of insulin reflecting its ability to regulate circulating levels of blood glucose?
A) brain
B) heart
C) kidney
D) skeletal muscle
E) testis

Question

Quizplus · Accepted Answer

Skeletal muscle is a major target tissue for insulin, as it plays a significant role in glucose uptake and utilization, thereby helping to regulate blood glucose levels.  The primary targets of insulin action, at the level of glucose homeostasis, are adipose tissue and skeletal muscle. Both of these tissues express GLUT4 which is stimulated to migrate to the plasma membrane in response to insulin action resulting in increased glucose disposal from the blood. Since the overall cellular mass of skeletal muscle is so large, in relation to all other tissues, insulin-mediated glucose uptake into this tissue represents one of the major glucose-lowering effects of the hormone

Which of the Following Represents a Major Target Tissue for the Action