You are testing the effects, on insulin function, to the addition of an unknown substance to adipocytes in culture. In the presence or absence of the compound you find that insulin binds to the adipocytes with equal affinity. Insulin alone results in a 5-fold increase in the rate of glucose uptake, above the basal rate. However, following addition of your test compound the rate of glucose uptake in response to insulin is only 0.5-fold above the basal rate. Your compound is actively taken up by the adipocytes and thus is likely exerting its effects intracellularly. Which of the following substances is your test compound most likely mimicking in this cell culture system?
A) ceramide
B) glucuronate
C) glucosamine
D) glucose
E) phosphatidic acid
Correct Answer:
Verified
Q1: A 19-year-old man is brought to the
Q3: Addition of which of the following compounds
Q4: Type 1 diabetics frequently experience ketoacidosis. Administration
Q5: A 13-year-old adolescent boy with type 1
Q6: Pancreatic oxidation of glucose results in increased
Q7: Recent evidence has identified an enzyme involved
Q8: Insulin action results in the increased expression
Q9: Insulin, being a growth factor, increases the
Q10: Which of the following represents a major
Q11: Activation of insulin receptors by binding of
Unlock this Answer For Free Now!
View this answer and more for free by performing one of the following actions
Scan the QR code to install the App and get 2 free unlocks
Unlock quizzes for free by uploading documents