You are comparing the responses of 2 strains of mice to the effects of a high-fat diet. Your observations show that although both strains become obese on the diet, one strain has a much higher level of insulin resistance associated with the diet-induced obesity. This latter strain of mice would most likely be shown to have significantly increased levels of secretion of which of the following adipokines?
A) adiponectin
B) adipsin
C) leptin
D) resistin
E) vaspin

Question

Quizplus · Accepted Answer

Resistin is an adipokine that is associated with increased insulin resistance. The strain of mice with higher insulin resistance would likely have increased levels of resistin.  Resistin is a 12-kDa protein produced by adipocytes and macrophages that induces insulin resistance. Thus the higher the level of resistin secreted, the higher the level of insulin resistance.

You Are Comparing the Responses of 2 Strains of Mice