A patient is diagnosed with problems in emptying the gallbladder. On a blood checkup, one hormone/peptide that is known to stimulate gallbladder contraction is inappropriately low. Which of the following hormones is most likely deficient leading to the observed symptoms?
A) cholecystokinin, CCK
B) gastrin
C) GLP-1
D) pancreatic polypeptide
E) peptide tyrosine tyrosine, PYY

Question

Quizplus · Accepted Answer

Cholecystokinin (CCK) is the hormone responsible for stimulating gallbladder contraction and bile release. A deficiency in CCK would lead to problems in emptying the gallbladder.  Cholecystokinin (CCK) is secreted from intestinal enteroendocrine I cells predominantly in the duodenum and jejunum. The level of CCK in the blood rises within 15 minutes of food ingestion and reaches a peak by 25 minutes. Upon binding its receptors in the gut, CCK induces contractions of the gallbladder and release of pancreatic enzymes and also inhibits gastric emptying.

A Patient Is Diagnosed with Problems in Emptying the Gallbladder