Telomerase is the specialized activity that allows for replication of the telomeric ends of the chromosomes. In addition to an RNA that is complimentary to the telomeric repeat sequence what other component is required of this complex for its normal activity?
A) DNA-dependent DNA polymerase
B) DNA-dependent RNA polymerase
C) DNA helicase
D) RNA-dependent DNA polymerase
E) RNA-dependent RNA polymerase

Question

Quizplus · Accepted Answer

Telomerase requires an RNA-dependent DNA polymerase, also known as reverse transcriptase, to synthesize DNA from its RNA template to extend the telomeres.  Telomerase is a complex composed of several proteins, an RNA with sequence complimentary to the telomeric repeats, and a reverse transcriptase activity that extends the 3′-end of the lagging strands using the telomerase RNA as the template. The reverse transcriptase activity of telomerase is encoded by the TERT gene (telomerase reverse transcriptase). Reverse transcriptases are RNA-dependent DNA polymerases.

Telomerase Is the Specialized Activity That Allows for Replication of the Telomeric