Question 1

What advantages does dioxygen have over nitrate, ferric ion, carbon dioxide, sulfate and sulfur as final electron acceptors in the electron transport system?

Accepted Answer

The answer of What advantages does dioxygen have over nitrate,...

Question 2

Describe the mechanism whereby uncoupling agents disrupt phosphorylation.

Accepted Answer

The answer of Describe the mechanism whereby uncoupling agents disrupt...

Question 3

The electron transport system consists of a series of oxidations rather than one reaction. Why is this an important feature of energy capture?

Accepted Answer

The answer of The electron transport system consists of a...

Question 4

Describe the role of UCP1 in nonshivering thermogenesis.

Accepted Answer

The answer of Describe the role of UCP1 in nonshivering...

Question 5

What is the respirasome?

Accepted Answer

The answer of What is the respirasome?...

Question 6

A previous explanation of the mechanism of ATP synthesis referred to as the chemical coupling hypothesis, postulated that ATP synthesis occurs as s substrate level phosphorylation via a phosphate containing intermediate. The chemical coupling hypothesis failed to explain why mitochondrial membrane must be intact during ATP synthesis. How does the chemiosmotic theory account for this phenomena?

Accepted Answer

The answer of A previous explanation of the mechanism of...

Question 7

Valinomycin is an ionophore antibiotic that renders biological membranes permeable to K⁺. Its side effects in patients with bacterial infections include a rise in body temperature and sweating. Explain.

Accepted Answer

The answer of Valinomycin is an ionophore antibiotic that renders...

Question 8

When taken in appropriate amounts Vitamin E protects the body from ROS. However when it is taken in excessive amounts Vitamin E can potentially make the body more susceptible to ROS. Explain.

Accepted Answer

The answer of When taken in appropriate amounts Vitamin E...

Question 9

Proteins with ionizable cysteine thiol groups undergo reversible redox reactions. These proteins are referred to collectively as the cysteine proteome. Discuss the role of redox switches in the context of the cysteine proteome.

Accepted Answer

The answer of Proteins with ionizable cysteine thiol groups undergo...

Question 10

According to the chemiosmotic theory, what would be the effect on oxidative phosphorylation of allowing other positive ions to diffuse across the inner mitochondrial membrane?

Accepted Answer

The answer of According to the chemiosmotic theory, what would...

Question 11

Cyanide causes an irreversible inhibition of electron transport that prevents ATP synthesis, whereas the inhibitory effect of small amounts of dinitrophenol on ATP synthesis is reversible. Explain the difference.

Accepted Answer

The answer of Cyanide causes an irreversible inhibition of electron...

Question 12

Explain why an inhibitor of complex I will not only cause an increase in the ratio of NADH to NAD⁺ but also an increase in the UQ/UQH ratio.

Accepted Answer

The answer of Explain why an inhibitor of complex I...

Question 13

Suppose that the mitochondrial complexes were not imbedded within the inner mitochondrial membrane. According to the chemiosmotic theory, what would be the consequences?

Accepted Answer

The answer of Suppose that the mitochondrial complexes were not...

Question 14

What is the minimum voltage drop for individual electron transfer events in the mitochondrial electron transport system that is necessary for ATP synthesis?

Accepted Answer

The answer of What is the minimum voltage drop for...

Question 15

Ethanol is oxidized in the liver to form acetate, which is converted to acetyl-CoA. Determine how many molecules of ATP are produced from one mole of ethanol. Note that 2 mol of NADH are produced when ethanol is oxidized to form acetate.

Accepted Answer

The answer of Ethanol is oxidized in the liver to...

Quiz 10: Aerobic Metabolism II: Electron Transport and Oxidative Phosphorylation