Insulin is a protein hormone that helps to control the level of glucose in the blood. It is secreted from specialized cells in the pancreas. Based on this information, which path does insulin take out of the cell?
A)ER membrane $\rightarrow$ vesicle membrane $\rightarrow$ plasma membrane $\rightarrow$ exterior of cell
B)vesicle $\rightarrow$ ER $\rightarrow$ Golgi apparatus$\rightarrow$ exterior of cell
C)nucleus $\rightarrow$ ER $\rightarrow$ Golgi apparatus $\rightarrow$ vesicle $\rightarrow$ exterior of cell
D)ER $\rightarrow$ Golgi apparatus $\rightarrow$ vesicle $\rightarrow$ exterior of cell
E)ER $\rightarrow$ nucleus $\rightarrow$ cytosol $\rightarrow$ exterior of cell

Question

Insulin is a protein hormone that helps to control the level of glucose in the blood. It is secreted from specialized cells in the pancreas. Based on this information, which path does insulin take out of the cell?
A)ER membrane $\rightarrow$  vesicle membrane $\rightarrow$  plasma membrane $\rightarrow$ exterior of cell
B)vesicle $\rightarrow$  ER $\rightarrow$  Golgi apparatus$\rightarrow$  exterior of cell
C)nucleus $\rightarrow$ ER $\rightarrow$  Golgi apparatus $\rightarrow$  vesicle $\rightarrow$  exterior of cell
D)ER $\rightarrow$  Golgi apparatus $\rightarrow$  vesicle $\rightarrow$  exterior of cell
E)ER $\rightarrow$  nucleus $\rightarrow$  cytosol $\rightarrow$ exterior of cell

Quizplus · Accepted Answer

Insulin is synthesized in the rough endoplasmic reticulum (ER), processed in the Golgi apparatus, and packaged into vesicles for secretion outside the cell. Therefore, insulin travels from the ER to the Golgi apparatus to a vesicle, and finally is secreted to the exterior of the cell. Choice D is the only option that follows this path.

Insulin Is a Protein Hormone That Helps to Control the Level