You are investigating a particular cell type, and you notice that a protein normally found in the lysosome ends up being secreted from the cell. This appears to be the only thing wrong with these cells. Of the following conditions, which is the MOST likely cause of this defect in these cells?
A)The lysosome leaks the protein out of the cell.
B)One of the signal sequences on the lysosomal protein is defective.
C)Transport vesicles responsible for sorting in the cell are defective.
D)The pH of the lysosome is not low enough for the protein to remain in it.

Question

Quizplus · Accepted Answer

Lysosomal proteins have signal sequences that direct them to the lysosome for sorting and eventual degradation. If one of these signal sequences is defective, the protein may not be properly sorted and could end up being secreted from the cell. The other options (A, C, and D) do not directly relate to the lysosomal sorting mechanism and are less likely to cause this specific defect.

You Are Investigating a Particular Cell Type, and You Notice