Which type of cell-surface receptor undergoes changes in phosphorylation in response to binding of its ligand?
A)G protein-coupled receptor
B)receptor kinase
C)ligand-gated ion channel
D)both the G protein-coupled receptor and the receptor kinase

Question

Quizplus · Accepted Answer

Receptor kinases are enzymes that have both receptor and kinase activity. They undergo changes in phosphorylation upon ligand binding, which allows them to signal cascades of intracellular responses. In contrast, G protein-coupled receptors activate cascades by interacting with G proteins, which do not directly undergo phosphorylation in response to ligand binding. Ligand-gated ion channels open or close in response to the binding of their ligand, but they do not undergo changes in phosphorylation.

Which Type of Cell-Surface Receptor Undergoes Changes in Phosphorylation in Response