In the context of approaches to gene identification and discovery, ________, in which the goal is to discover the location of a gene (or genes) in relation to a marker gene (whose position is already known), is often used to search for disease-related genes.
A) the Thousand Genomes Project
B) genome-wide association
C) linkage analysis
D) next-generation sequencing

Question

Quizplus · Accepted Answer

Linkage analysis is a method of gene mapping that is used to identify the location of disease-related genes by studying their patterns of inheritance within families. It involves comparing the frequency of a trait (such as a disease) with the presence of certain genetic markers (such as SNPs) in family members. By identifying genetic markers that are closely linked to the disease-causing gene, researchers can narrow down the region of the genome where the gene is likely to be located.

In the Context of Approaches to Gene Identification and Discovery