Binding of a signalling molecule to which type of receptor leads directly to a change in the distribution of ions on opposite sides of the membrane?
A) receptor tyrosine kinase
B) G protein-coupled receptor
C) ligand-gated ion channel
D) steroid receptor

Question

Quizplus · Accepted Answer

Ligand-gated ion channels open or close in response to binding of a specific signalling molecule, which leads to a change in ion distribution on opposite sides of the plasma membrane. This change in ion distribution can generate an electrical signal in cells such as neurons and muscles, which is important for transmitting information and controlling physiological processes. Receptor tyrosine kinases and G protein-coupled receptors activate intracellular signalling pathways through second messengers, while steroid receptors modulate gene transcription.

Binding of a Signalling Molecule to Which Type of Receptor