What is the role of DNA ligase in the elongation of the lagging strand during DNA replication?
A) It synthesises RNA nucleotides to make a primer.
B) It joins Okazaki fragments together.
C) It unwinds the parental double helix.
D) It stabilises the unwound parental DNA.

Question

Quizplus · Accepted Answer

DNA ligase plays a crucial role in the elongation of the lagging strand during DNA replication by joining together the Okazaki fragments that are synthesized discontinuously by DNA polymerase III. Without ligase, the fragments would remain separate and the lagging strand would not be able to fully replicate.

What Is the Role of DNA Ligase in the Elongation