Which of the following is an example of cooperativity?
A) binding of an ATP molecule along with another substrate in an active site
B) binding of a molecule to one subunit of a tetramer, which promotes faster binding to each of the other three subunits
C) the product of one enzyme in a metabolic pathway serving as the substrate for the next enzyme in the pathway
D) binding of the end product of a metabolic pathway to the enzyme that catalyzes the first step in the pathway

Question

Quizplus · Accepted Answer

Cooperativity occurs when the binding of a molecule to one subunit of a multimeric protein affects the binding of other subunits. In this case, the binding of a molecule to one subunit promotes faster binding to each of the other three subunits, demonstrating cooperativity. The other choices do not involve cooperativity.

Which of the Following Is an Example of Cooperativity