The protein complex that activates progress through the M phase checkpoint will allow which of the following to occur?
A) cleavage of cohesin proteins by separase
B) modification of separase by cohesins
C) disassembly of spindle microtubules at the centromere
D) assembly of spindle microtubules

Question

Quizplus · Accepted Answer

The protein complex that activates progress through the M phase checkpoint (known as the APC/C complex) triggers the destruction of cyclins, which in turn activates the enzyme separase. Activated separase then cleaves the cohesin proteins that hold the sister chromatids together, allowing the chromatids to separate and move toward opposite poles of the cell.

The Protein Complex That Activates Progress Through the M Phase