Cells from advanced malignant tumors frequently have very abnormal chromosomes as well as an abnormal number of chromosomes.What might explain the association between malignant tumors and chromosomal abnormalities?
A)Cancer cells replicate chromosomes multiple times per cell cycle.
B)Cancer cells are no longer anchorage dependent.
C)Cell cycle checkpoints are not in place to stop cells with chromosome abnormalities.
D)Cells with abnormal chromosomes have increased metabolism.

Question

Quizplus · Accepted Answer

One of the functions of cell cycle checkpoints is to ensure the proper replication and division of chromosomes. If these checkpoints fail or are not present, cells with chromosomal abnormalities may continue to divide and accumulate further abnormalities, which can lead to the development of a malignant tumor.

Cells from Advanced Malignant Tumors Frequently Have Very Abnormal Chromosomes