Researchers established a number of cultured cell lines derived from different tumors.How might they determine which ones are malignant?
A)Identify the ones that grow in a single layer in culture.
B)Identify the ones with elevated rates of apoptosis.
C)Identify the ones with aberrant chromosome number or structure.
D)Identify the ones with elongated cell cycles.

Question

Quizplus · Accepted Answer

Aberrant chromosome number or structure is a hallmark of malignant tumors. Therefore, identifying cultured cell lines with such abnormalities would indicate malignancy. The other options may not necessarily be indicative of malignancy. Single-layer growth can be observed in both malignant and benign tumors. Elevated rates of apoptosis can occur in response to various stimuli and may not be specific to malignant tumors. Elongated cell cycles can be a characteristic of some benign tumors.

Researchers Established a Number of Cultured Cell Lines Derived from Different