An inhibitor that must be metabolized by the enzyme before it becomes covalently attached to the enzyme is called a mechanism-based inhibitor. What is another term that has been used for such an inhibitor?
A) Noncompetitive
B) Suicide
C) Terminal
D) Transition State
E) Turnover

Question

Quizplus · Accepted Answer

The term "suicide" has also been used to describe mechanism-based inhibitors because they irreversibly destroy the enzyme once metabolized and covalently bind to it.

An Inhibitor That Must Be Metabolized by the Enzyme Before