What is the condition under which an enzyme is defined as having a "ping-pong" mechanism?
A) Enzyme (or enzyme/prosthetic group) is modified by substrate
B) The enzyme has a dissociable coenzyme
C) The first substrate on and the last product off show competitive binding
D) The reaction is bimolecular
E) The two substrates bind in a random order

Question

Quizplus · Accepted Answer

The "ping-pong" mechanism involves an enzyme being temporarily modified by the first substrate, which leaves before the second substrate binds. This is characteristic of enzymes where the enzyme or an enzyme-bound prosthetic group is modified as part of the reaction mechanism, often seen in transferase enzymes.

What Is the Condition Under Which an Enzyme Is Defined