Which of the following is TRUE of Fc receptors for immunoglobulins?
A) They are found on cells of the reticuloendothelial system and are involved in antibody-dependent, cell-mediated cytotoxicity.
B) They are associated with the T3 complex of the T-cell receptor.
C) They are not able to bind immunoglobulin.
D) They are receptors which recognize the Fab portion of the antibody.
E) They are all unique, because each has a specific antigen binding capacity.

Question

Quizplus · Accepted Answer

Fc receptors for immunoglobulins are found on cells of the reticuloendothelial system and play a role in antibody-dependent, cell-mediated cytotoxicity. They recognize and bind to the Fc (constant) region of antibodies, not the Fab (variable) region, which is involved in antigen binding. They are not associated with the T3 complex of the T-cell receptor, nor do they have specific antigen binding capacities themselves; that function is reserved for the variable regions of antibodies.

Which of the Following Is TRUE of Fc Receptors for Immunoglobulins