Suppose that you have the situation that the P site of the prokaryotic ribosome contains a tRNA to which is attached a peptidyl chain, and the A site contains a tRNA to which is attached an amino acid. What is the next step?
A) translocation of the mRNA relative to the ribosome by one codon
B) peptide bond synthesis
C) dissociation of the tRNA in the P site to allow movement of the tRNA from the A site to the P site
D) binding of a new aminoacyl-tRNA to the ribosome catalyzed by Tu
E) hydrolysis of the peptidyl chain from the tRNA

Question

Quizplus · Accepted Answer

The next step is peptide bond synthesis between the amino acid on the tRNA in the A site and the peptidyl chain on the tRNA in the P site. This reaction is catalyzed by peptidyl transferase, which is a component of the large subunit of the ribosome. Once the peptide bond is formed, the tRNA in the P site will now have the amino acid attached to it and move to the E site for release, while the tRNA in the A site will now have the peptidyl chain attached to it and move to the P site. This step is critical for protein synthesis, as it elongates the growing polypeptide chain.

Suppose That You Have the Situation That the P Site