Which of the following statements is(are) TRUE?
A) proinsulin is the first polypeptide intermediate in insulin biosynthesis
B) insulin has two disulfide bridges which may be reduced with full retention of activity
C) C-peptide is secreted in equimolar amounts as insulin
D) insulin must undergo post-translational modification
E) none of the above

Question

Quizplus · Accepted Answer

C-peptide is a byproduct of insulin synthesis and is secreted in equimolar amounts as insulin. The other statements are false. Proinsulin is the intermediate in insulin biosynthesis, insulin has three disulfide bridges, and insulin does undergo post-translational modification.

Which of the Following Statements Is(are) TRUE