Regarding nucleosome structure, which of the following statements is correct?
A) Nucleosomes are spherical structures comprised of RNA, nonhistone proteins and histone proteins.
B) The major histones comprising nucleosomes are H1 and H4.
C) Nucleosomes permit efficient packing of DNA to about one seventh its normal length.
D) The histone associated with the DNA in the linker region holding nucleosomes is called H2A.
E) All of the above.

Question

Quizplus · Accepted Answer

Nucleosomes consist of histone proteins (H2A, H2B, H3, H4) organized as an octamer around which DNA is wrapped. This allows for efficient packing of DNA to about one seventh of its normal length, which is essential for proper chromosomal organization and function. A is incorrect because nucleosomes do not contain RNA. B is incorrect because while H1 and H4 are major histones, all four histones are necessary for nucleosome formation. D is incorrect because the histone associated with the DNA in the linker region is H1, not H2A.

Regarding Nucleosome Structure, Which of the Following Statements Is Correct