Eukaryotic RNA polymerase II differs from the prokaryotic RNA polymerase because it
A) retains sigma factor during elongation.
B) can incorporate either deoxy- or ribonucleotide precursors.
C) requires multiple accessory proteins.
D) transcribes only ribosomal RNA genes.
E) interacts directly with the termination factor rho.

Question

Quizplus · Accepted Answer

Eukaryotic RNA polymerase II requires multiple accessory proteins, whereas prokaryotic RNA polymerase does not.

(Note: A is incorrect because sigma factor is associated with prokaryotic RNA polymerase, not eukaryotic RNA polymerase II. B is incorrect because both prokaryotic and eukaryotic RNA polymerases can incorporate ribonucleotide precursors. D is incorrect because eukaryotic RNA polymerase II transcribes all protein-coding genes, not just ribosomal RNA genes. E is incorrect because termination in eukaryotes is typically mediated by different factors than in prokaryotes; eukaryotic RNA polymerase II interacts with a termination factor called TTF-I.)

Eukaryotic RNA Polymerase II Differs from the Prokaryotic RNA Polymerase