alpha-Amanitin is toxic to eukaryotic cells because it
A) prevents translocation of mRNA from the nucleus to the cytoplasm.
B) causes spliceosome assembly defects.
C) causes ribosome assembly defects.
D) causes protein transport defects.
E) inhibits RNA polymerase II.

Question

Quizplus · Accepted Answer

alpha-Amanitin inhibits RNA polymerase II, which is responsible for transcribing genes into mRNA. Therefore, it prevents the production of mRNA and subsequent translation of proteins, leading to cell death.

Alpha-Amanitin Is Toxic to Eukaryotic Cells Because It