The largest part of the driving force causing protein chains to fold into compact, globular structures is typically
A) electrostatic force.
B) hydrogen bonding.
C) hydrophobic bonding.
D) polar group interaction.
E) alpha helix formation.

Question

Quizplus · Accepted Answer

Hydrophobic bonding is typically the largest driving force causing protein chains to fold into compact, globular structures. This is because nonpolar amino acid side chains tend to aggregate together, away from the surrounding water, which drives the folding of the protein. Electrostatic force, hydrogen bonding, and polar group interactions can contribute to the stability of the folded protein, but they are not typically the primary driving force for the folding process. Alpha helix formation is a specific secondary structure within a folded protein and not a driving force for the folding process itself.

The Largest Part of the Driving Force Causing Protein Chains