Which of the following amino acids will terminate an alpha helical structure in globular proteins?
A) Tryptophan
B) Proline
C) Tyrosine
D) Histidine
E) Isoleucine

Question

Quizplus · Accepted Answer

Proline is known to introduce a kink in the polypeptide chain due to its rigid cyclic structure, which disrupts alpha helices and beta sheets. Therefore, it is the amino acid that is most likely to terminate an alpha helix in a globular protein.

Which of the Following Amino Acids Will Terminate an Alpha