Regulatory transcription factors ________.
A) influence the binding of sigma factor to DNA
B) influence the assembly of the basal transcription complex
C) influence the degree of unwinding of DNA at the promoter
D) open the two strands of DNA so that RNA polymerase can begin transcription

Question

Quizplus · Accepted Answer

Regulatory transcription factors influence the assembly of the basal transcription complex by recruiting and interacting with other transcriptional machinery components. Choice A is incorrect because sigma factors are part of bacterial RNA polymerase holoenzyme and are not involved in eukaryotic transcription. Choice C is incorrect because the degree of unwinding of DNA at the promoter is mainly determined by the RNA polymerase itself. Choice D is incorrect because regulatory transcription factors do not directly open the two strands of DNA.

Regulatory Transcription Factors ________