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-One of her colleagues suggested she try increased methylation of C nucleotides in the DNA of promoters of a mammalian system. Which of the following results would she most likely see?
A) decreased chromatin condensation
B) activation of histone tails for enzymatic function
C) higher levels of transcription of certain genes
D) inactivation of the selected genes

Question

Quizplus · Accepted Answer

Increased methylation of C nucleotides in the DNA of promoters of a mammalian system usually results in the inactivation of selected genes. Methylation of promoter regions can prevent the binding of transcription factors required for gene expression, leading to reduced transcription levels.

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