If the concentration of a ligand is 100 times greater than the Kd of its receptor,
A)half of the receptors will be bound to a ligand.
B)few of the receptors will be bound to a ligand.
C)none of the receptors will be bound to a ligand.
D)most of the receptors will be bound to a liganD.

Question

Quizplus · Accepted Answer

According to the rule of thumb, if the concentration of ligand is 100 times greater than the Kd value of its receptor, most of the receptors (approx. 99%) will be saturated with the ligand, resulting in a high proportion of bound receptors. Therefore, option D - most of the receptors will be bound to a ligand - is the correct choice.

If the Concentration of a Ligand Is 100 Times Greater