G-protein coupled,enzyme-linked,and ligand-gated ion channel receptors are similar in that they
A)associate with a protein bound to GDP or GTP.
B)are all linked to protein kinase activation.
C)change their conformation when bound to a hormone.
D)bind similar hormones.
E)open ion channels.

Question

Quizplus · Accepted Answer

All three types of receptors change their conformation when bound to a hormone, leading to downstream signaling events. However, they differ in their mechanism of action. G-protein coupled receptors initiate signaling through the activation of intracellular G proteins, enzyme-linked receptors activate downstream enzymes, and ligand-gated ion channels directly open ion channels in the plasma membrane. Therefore, options A, B, D, and E are not accurate statements about all three types of receptors.

G-Protein Coupled,enzyme-Linked,and Ligand-Gated Ion Channel Receptors Are Similar in That