Aldosterone synthesis and secretion are primarily regulated by the:
A) liver.
B) renin-angiotensin system.
C) adrenal glands.
D) hypothalamus.

Question

Quizplus · Accepted Answer

The renin-angiotensin system plays a major role in regulating aldosterone synthesis and secretion. Renin, released by the kidneys in response to decreased blood pressure or volume, reacts with angiotensinogen to form angiotensin I. Angiotensin-converting enzyme (ACE), primarily located in the lungs, converts angiotensin I to angiotensin II, which stimulates the adrenal cortex to produce and release aldosterone.

Aldosterone Synthesis and Secretion Are Primarily Regulated by The