Like Listeria,other bacterial pathogens have also evolved to take advantage of actin-based cell motility systems in their hosts.For example,some pathogenic strains of E.coli make a cytotoxic factor (CNF1)that converts a specific glutamine residue on RhoGTPases to glutamate.This change blocks both the intrinsic and GAP-stimulated GTP hydrolysis activity of the Rho protein.Predict the effects of CNF1 on human epithelial cells in culture.

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The Answer of Like Listeria,other bacterial pathogens have also evolved to take advantage of actin-based cell motility systems in their hosts.For example,some pathogenic strains of E.coli make a cytotoxic factor (CNF1)that converts a specific glutamine residue on RhoGTPases to glutamate.This change blocks both the intrinsic and GAP-stimulated GTP hydrolysis activity of the Rho protein.Predict the effects of CNF1 on human epithelial cells in culture.

Like Listeria,other Bacterial Pathogens Have Also Evolved to Take Advantage