In muscle cells,the following reaction proceeds as written,i.e.,from left to right,despite having DG°' » +30 kJ/mol.How can this occur? malate + NAD⁺ oxaloacetate + NADH + H⁺ A) It is obviously thermodynamically favored under standard conditions. B) In the cell, it is kinetically favored, even though it's thermodynamically unfavored. C) The concentration of malate must be higher than oxaloacetate for this reaction to occur in the cell. D) [H⁺] must be higher in muscle than under standard conditions, thus altering DG°' to DG°.

Question

Quizplus · Accepted Answer

The reaction can proceed in the cell because the concentration of malate is higher than that of oxaloacetate, driving the reaction forward despite the unfavorable standard Gibbs free energy change.

In Muscle Cells,the Following Reaction Proceeds as Written,i