When the citric acid cycle is not functioning, the most common fate of acetyl-CoA from sugar metabolism in humans is the formation of fatty acids or cholesterol.

Question

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When the citric acid cycle is not functioning or is overloaded, acetyl-CoA from sugar metabolism can be diverted towards the synthesis of fatty acids or cholesterol, as these pathways provide alternative routes for the utilization of acetyl-CoA.

When the Citric Acid Cycle Is Not Functioning, the Most